Process for producing bacterial cells having a high content...

Details Process for producing bacterial cells having a high content... Process for producing bacterial cells having a high content...

C - Chemistry, Metallurgy

12

N

195/49

C12N 1/20 (2006.01) C12N 9/12 (2006.01)

Patent

CA 1156576

ABSTRACT OF THE DISCLOSURE A process is described for cultivating thermophilic bacteria of the genus Bacillus having the ability to produce acetate kinase, wherein said cultivation is carried out con- tinuously at a dilution rate (D) in the range from about 0.9 µmax to 1.0 µmax, wherein D is the dilution rate (1/hr), and µmax is the maximum specific growth rate (1/hr), to thereby produce bacterial cells having a high content of acetate kinase. The bacterial cells cultivated and harvested by this process have a higher content of acetate kinase per gram of dry cells than bacterial cells obtained by a batch process, and the quantity of cells produced is also high.

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