Process for producing carotenoid compound

Details Process for producing carotenoid compound Process for producing carotenoid compound

C - Chemistry, Metallurgy

12

P

C12P 23/00 (2006.01) A23L 1/275 (2006.01) A23L 1/30 (2006.01) C12N 15/01 (2006.01) C12P 5/02 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2539069

The present invention relates to a process for producing zeaxanthin, .beta.- carotene, or lycopene, comprising inducing mutation in a carotenoid-producing microorganism in which the base sequence of DNA corresponding to 16S ribosomal RNA is substantially homologous to the base sequence described in SEQ ID NO: 1; screening for a mutant strain having a high product proportion of zeaxanthin, .beta.-carotene, or lycopene to the whole production amount of carotenoids to provide a microorganism producing zeaxanthin, .beta.-carotene, or lycopene; culturing the mutant microorganism; and harvesting zeaxanthin, .beta.- carotene, lycopene or a carotenoid mixture containing the same from the resultant culture.

La présente invention concerne un procédé de production de zéaxantine, de beta -carotène ou de lycopène qui consiste à mutagéniser un micro-organisme produisant un caroténoïde dont la séquence de bases d'ADN correspondant à l'ARN ribosomique 16S est sensiblement homologue à la séquence de bases représentée par SEQ ID NO : 1, à sélectionner un mutant présentant un taux élevé de zéaxantine, de beta -carotène ou de lycopène dans le produit de caroténoïde total de manière à obtenir une souche productrice de zéaxantine, de beta -carotène ou de lycopène, à cultiver le mutant, puis à récolter la zéaxantine, le beta -carotène ou le lycopène ou un mélange de caroténoïdes contenant ceux-ci à partir de la culture ainsi produite.

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