Process for producing cephalosporins

C - Chemistry – Metallurgy – 07 – D

Patent

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260/104, 260/101

C07D 501/20 (2006.01) C07D 277/20 (2006.01) C07D 501/59 (2006.01) C07F 9/02 (2006.01) C07F 9/6539 (2006.01)

Patent

CA 1229847

ABSTRACT OF THE DISCLOSURE This invention relates to a novel process for producing a useful cephalosporin which comprises reacting a thiolo ester compound with a 7-aminocephalosporin in the presence of boron trifluoride or a complex compound thereof. This process enables the cephalosporin to be produced with a high purity in a high yield.

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