Process for producing coenzyme q10

Details Process for producing coenzyme q10 Process for producing coenzyme q10

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) C12N 1/21 (2006.01) C12N 9/10 (2006.01) C12N 9/12 (2006.01) C12P 7/66 (2006.01)

Patent

CA 2432079

A process for efficiently producing coenzyme Q~10 by using microorganisms wherein coenzyme Q~10 side-chain synthesis genes originating in fungi belonging to the genera Aspergillus andLeucosporidium are used. DNA having a DNA sequence represented by SEQ ID NO:1 or 2 or a DNA sequence derived therefrom by deletion, addition, insertion or substitution of one or more bases and encoding a protein having a decaprenyl diphosphate synthase activity.

L'invention concerne un procédé relatif à la production efficace de coenzyme Q10, qui consiste à utiliser des microorganismes. On fait appel aux gènes de synthèse de chaîne latérale de coenzyme Q10 apparaissant dans les champignons du genre Aspergillus ou Leucosporidium . L'invention concerne également de l'ADN qui comporte une séquence d'ADN représentée par le numéro de séquence SEQ ID N0: 1 ou 2, ou bien une séquence d'ADN dérivée de la séquence considérée, par suppression, adjonction, insertion ou substitution d'une ou plusieurs bases, et codant une protéine à activité de décaprényl diphosphate synthase.

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