Process for producing detoxified pharmaceutical products...

A - Human Necessities – 61 – K

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A61K 31/095 (2006.01) A61K 31/185 (2006.01) A61K 31/66 (2006.01) A61K 31/675 (2006.01)

Patent

CA 1121727

PROCESS FOR PRODUCING DETOXIFIED PHARMACEUTICAL PRODUCTS CONTAINING A CYTOSTATICALLY ACTIVE ALKYLATING AGENT ABSTRACT OF DISCLOSURE The present invention is related to the detoxification of cytostatically active alkylating agents causing undesired urotoxic side effects in the kidneys, the urinary tracts and the urinary bladder of the patients treated therewith by administering the alkylating agent in combination with a pharmacologically acceptable salt of a dithiodi-(alkane sulfonic acid) of the general formula Image . The present invention is further related to detoxified pharmaceutical products containing such cytostatically active alkylating agents and process for producing the same.

321645

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