Process for producing glycosides

C - Chemistry – Metallurgy – 12 – P

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C12P 19/14 (2006.01) C07H 3/06 (2006.01) C07H 15/04 (2006.01) C07H 15/08 (2006.01)

Patent

CA 2381856

A process for efficiently and economically producing a lactosyl glycoside and an N-acetyllactsaminyl glycoside, which are useful as foods, functional food materials, drugs and reagents, by using a transfer reaction represented by the following general formula in the presence of an enzyme having an activity of cleaving a .beta.1,4 glycosyl bond: LacA-X + Y .fwdarw. LacA-Y + X wherein LacA represents lactose or N-acetyllactosamine; X represents hydrogen (H), a saccharide, a glycoconjugate or a phenolic compound; and Y represents a compound having alcoholic hydroxy or phenolic hydroxy.

L'invention concerne un procédé destiné à produire de manière efficace et économique un glycoside lactosyle et un glycoside N-acétyllactsaminyle, utiles comme aliments, comme matières fonctionnelles pour produits alimentaires, comme médicaments et comme réactifs, en utilisant une réaction de transfert représentée par la formule générale suivante en présence d'une enzyme ayant une activité de clivage d'une liaison glycosyle .beta.-1,4 : LacA-X + Y LacA Y + X, dans laquelle LacA représente un lactose ou un groupe N-acétyllactsaminyle, X représente un hydrogène (H), un saccharide, un glycoconjugué ou un composé phénolique, et Y représente un composé renfermant un groupe hydroxyle alcoolique ou un groupe hydroxy phénolique.

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