Process for producing haloalkyl alkanoates

Details Process for producing haloalkyl alkanoates Process for producing haloalkyl alkanoates

C - Chemistry, Metallurgy

07

C

260/493, 260/479

C07C 67/28 (2006.01) C07C 67/11 (2006.01) C07C 69/63 (2006.01)

Patent

CA 2019465

Shionogi Seiyaku Kabushiki Kaisha A process for producing haloalkyl alkanoates Inventors: Mamoru Tanaka Makoto Hajima, and Yoshio Hamashima - Abstract - A haloalkyl alkanoate (III) is useful as a reagent for preparing some oral antibacterials. The compound is now found to be preparable economically and safely by treating alkanoic acid salt (I) with 10 equivalents or more of dihaloalkane (II) in 2 to 5 parts by weight of alkanoic acid dialkylamide. Image (wherein R and R1 each is hydrogen or optionally substituted alkyl, M is a salt forming atom or group, and X and Hal each is halogen) -1-

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