Process for producing indolmycins

C - Chemistry – Metallurgy – 12 – N

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C12N 1/20 (2006.01) A01N 43/76 (2006.01) A01N 63/02 (2006.01) A61K 31/42 (2006.01) C07D 413/06 (2006.01) C12P 17/16 (2006.01) C12P 17/18 (2006.01)

Patent

CA 2338832

A microorganism capable of producing indolemycin and having a tryptophan analog-tolerance; and a process for efficiently producing indolemycin or its salt which comprises culturing this microorganism in a medium and then collecting the indolemycin or its salt thus produced and accumulated in the liquid culture.

L'invention se rapporte à un micro-organisme susceptible de produire de l'indolémycine et doté d'une tolérance aux analogues du tryptophane. Elle se rapporte également à un procédé permettant de produire efficacement de l'indolémycine ou des sels d'indolémycine et consistant à cultiver le micro-organisme dans un milieu de culture puis à recueillir l'indolémycine ou ses sels ainsi produits et accumulés dans le milieu de culture liquide.

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