Process for producing intravenous immune globulin

Details Process for producing intravenous immune globulin Process for producing intravenous immune globulin

A - Human Necessities

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A61K 39/395 (2006.01) A61K 35/14 (2006.01) C07K 16/06 (2006.01)

Patent

CA 1083959

Application for Letters Patent on an Invention Entitled: "PROCESS FOR PRODUCING INTRAVENOUS IMMUNE GLOBULIN" Abstract of the Disclosure: A process is provided for producing intravenous immune globulin which comprises adsorbing plasminogen from blood of a selected mammalian species on L-lysine agarose, washing the adsorbate and eluting the purified plasminogen, converting the plasminogen to plasmin, and incubating a mixture of the plasmin and homospecific immune globulin having anticomplementary activity so as to reduce the anticomplementary activity, adsorbing excess plasmin present in the mixture, and recovering the immune globulin from the mixture. SUMMARY AND DETAILED DESCRIPTION: - 1 -

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