C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 1/107 (2006.01) C07K 5/083 (2006.01) C07K 14/47 (2006.01) C07K 19/00 (2006.01) C12N 1/21 (2006.01) C12N 15/62 (2006.01) C12P 21/02 (2006.01) C12P 21/06 (2006.01)
Patent
CA 2394404
KiSS-1 peptide or its salt can be industrially produced on a mass scale by subjecting a fused protein or peptide, wherein KiSS-1 peptide is ligated to the N-end of a protein or a peptide having cysteine at the N-end, to the reaction of cleaving the peptide bond in the amino acid side of the cysteine residue.
L'invention concerne la peptide KiSS-1 ou son sel, que l'on peut produire à l'échelle industrielle en soumettant une protéine fusionnée ou une peptide, la peptide KiSS-1 étant ligaturée à l'extrémité N d'une protéine ou d'une peptide présentant une cystèine à ladite extrémité, à la réaction de clivage de la liaison peptide dans la partie acide aminé du résidu de cystéine.
Nishimura Osamu
Suenaga Masato
Yamada Takao
Fetherstonhaugh & Co.
Takeda Chemical Industries Ltd.
Takeda Pharmaceutical Company Limited
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