Process for producing kiss-1 peptide

Details Process for producing kiss-1 peptide Process for producing kiss-1 peptide

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 19/00 (2006.01) C12N 1/21 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2472423

KiSS-1 peptide or its salt can be industrially produced on a large scale by subjecting a fused protein or peptide, which has KiSS-1 peptide ligated to the N-end of a low-molecular weight peptide having cysteine at the N-end, to a reaction of cleaving the peptide bond in the amino acid side of the cysteine residue.

Il est possible de produire industriellement et à grande échelle le peptide KiSS-1 ou son sel en soumettant un peptide ou une protéine fusionnée, qui comporte un peptide KiSS-1 ligaturé à l'extrémité N d'un peptide de faible poids moléculaire porteur de cystéine en son extrémité N, à une réaction de clivage de la liaison peptide du côté acide aminé du résidu cystéine.

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