Process for producing –-l-aspartyl-l-phenylalanine methyl...

Details Process for producing –-l-aspartyl-l-phenylalanine methyl... Process for producing –-l-aspartyl-l-phenylalanine methyl...

C - Chemistry, Metallurgy

07

K

530/5.06

C07K 5/06 (2006.01) C07K 5/072 (2006.01)

Patent

CA 1315475

ABSTRACT A process for producing dry .alpha.-L-aspartyl-L-phenylalanine methyl ester having an improved solubility from wet crystals of .alpha.-L-aspartyl-L-phenylalanine methyl ester having a water content of at least 20% by weight, which comprises drying the wet crystals at a temperature of higher than 50°C to obtain moist crystals having a water content of less than 20 or more than 15% by weight, then drying the moist crystals at a temperature of not higher than 50°C to obtain semi-dry crystals having a water content of less than 5% by weight, and further drying the semi-dry crystals at a temperature of higher than 50°C to obtain dry crystals of .alpha.-L-aspartyl-L-phenylalanine methyl ester.

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