Process for producing methylcobalamin

Details Process for producing methylcobalamin Process for producing methylcobalamin

C - Chemistry, Metallurgy

07

H

C07H 23/00 (2006.01)

Patent

CA 2449480

The present invention provides a novel industrially excellent and ecological process for producing methylcobalamin which is useful as a medicament etc. More specifically, it provides a process for producing methylcobalamin by reducing cyanocobalamin or hydroxocobalamin in the presence of a reducing agent, and then methylating the reductant by adding a water-soluble methylating agent.

La présente invention concerne un nouveau procédé apte à une exploitation industrielle et écologique pour la production de méthylcobalamine utile dans la préparation de médicaments et analogues. Plus précisément, l'invention concerne un procédé de production de méthylcobalamine caractérisé en ce qu'il comporte la réduction de cyanocobalamine ou d'hydroxocobalamine en présence d'un agent réducteur et, subséquemment la réduction complète par l'adjonction d'un agent de méthylation hydrosoluble suivie d'une méthylation.

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