Process for producing methylcobalamin

Details Process for producing methylcobalamin Process for producing methylcobalamin

C - Chemistry, Metallurgy

07

H

C07H 23/00 (2006.01) A61K 31/714 (2006.01)

Patent

CA 2394155

The present invention provides an industrially excellent and novel process for producing methylcobalamin useful as medicines. Namely, it provides a process for producing methylcobalamin, which comprises the step of methylating cyanocobalamin or hydroxocobalamin in the presence of a reducing agent and a water-soluble methylating agent.

L'invention se rapporte à un nouveau procédé qui s'avère excellent d'un point de vue industriel pour la production de méthylcobalamine qui est utile en tant que médicament ou analogue. Ledit procédé se caractérise en ce qu'il consiste en une méthylation de cyanocobalamine ou d'hydroxycobalamine en présence d'un agent réducteur et d'un agent de méthylation soluble dans l'eau.

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