Process for producing microspheres

Details Process for producing microspheres Process for producing microspheres

A - Human Necessities

61

K

A61K 9/50 (2006.01) A61K 47/34 (2006.01) B01J 13/12 (2006.01) C08J 3/16 (2006.01)

Patent

CA 2405194

A process for producing microspheres, characterized by: adding a polymer solution comprising a drug, an in vivo degradable polymer, and a water- miscible good solvent (solvent (A)) for the polymer to a homogeneous liquid mixture comprising a solvent (solvent (B)) which is a poor solvent for the polymer and is miscible with the solvent (A) and a solvent (solvent (C)) which is a poor solvent for the polymer and is immiscible with the solvent (A); emulsifying the resultant mixture to prepare an emulsion in which the polymer solution forms a dispersed phase and the homogeneous liquid mixture forms a continuous phase; and removing the solvent (A) from the dispersed phase.

L'invention concerne un procédé de production de microsphères, qui consiste à ajouter une solution polymère comprenant un médicament, un polymère dégradable in vivo, et un bon solvant hydrosoluble (solvant (A)) pour le polymère à un mélange liquide homogène comprenant un solvant (solvant (B)) qui est un mauvais solvant pour le polymère et est miscible avec le solvant (A) et un solvant (solvant (C)) qui est un mauvais solvant pour le polymère et est non miscible avec le solvant (A); à émulsionner le mélange résultant afin de préparer une émulsion dans laquelle la solution polymère forme une phase dispersée et le mélange liquide homogène forme une phase continue; et à éliminer le solvant (A) de la phase dispersée.

Affiliated with

Also associated with

Rating

Process for producing microspheres does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for producing microspheres, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for producing microspheres will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2037160