Process for producing mitomycin a by fermentation

Details Process for producing mitomycin a by fermentation Process for producing mitomycin a by fermentation

C - Chemistry, Metallurgy

12

N

195/103, 195/34.

C12N 1/02 (2006.01) C07D 487/14 (2006.01) C12P 17/10 (2006.01) C12P 17/18 (2006.01)

Patent

CA 1193211

ABSTRACT A process for producing mitonmycin A by fermentation, which involves culturing a microorganism belonging to the genus Streptomyces, which is capable of producing mitomycin A and having at least one property of (1) deficiency in an ability to produce mitomycin C and (2) a resistance to tryptophan analog, in a culture medium forming and accummulating mitomycin A in the culture medium; and recovering mitomycin A therefrom.

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