Process for producing nucleosides

Details Process for producing nucleosides Process for producing nucleosides

C - Chemistry, Metallurgy

12

P

195/120, 195/39,

C12P 19/38 (2006.01) C12N 1/20 (2006.01) C12N 9/12 (2006.01)

Patent

CA 2028119

The present invention concerns a process for producing nucleosides by carrying out the reaction of a base donor, a saccharide residue donor and a phosphoric acid donor by the use of an enzyme preparation containing nucleoside phosphorylase, thereby forming an N-glycosidic bond between the base moiety of the base donor and the saccharide moiety of the saccharide residue donor, which comprises using, as the enzyme preparation containing nucleoside phosphorylase, a preparation derived from the cells of one or more kinds of microorganisms belonging to thermophiles of the genus Bacillus and having high nucleoside phosphorylase activity per unit cell weight.

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