Process for producing optically active alcohol and...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/53 (2006.01) C07C 55/08 (2006.01) C12P 7/04 (2006.01) C12P 7/40 (2006.01) C12P 7/44 (2006.01)

Patent

CA 2555317

A low-cost and efficient industrial process for producing (S)-2-pentanol, (S)- 2-hexanol, 1-methylalkylmalonic acid and 3-methylcarboxylic acid with high optical purity. There is provided a process for producing (S)-2-pentanol and (S)-2-hexanol, comprising causing a certain type of microbe or transformed cells, a treatment mixture from the microbe or cells, a culture solution of the microbe or cells and/or a product of crude purification or purification of a carbonyl reductase fraction obtained from the microbe or cells to act on 2- pentanone and 2-hexanone, respectively.

Procédé industriel à faible coût et rendement élevé pour produire du (S)-2-pentanol, du (S)-2-hexanol, de l'acide 1-méthylalkylmalonique et de l'acide 3-méthylcarboxylique avec une pureté optique élevée. Il est fourni un procédé pour produire du (S)-2-pentanol et du (S)-2-hexanol, comprenant de faire en sorte qu'un certain type de microbe ou de cellules transformées, un mélange de traitement provenant du microbe ou des cellules, une solution de culture du microbe ou des cellules et/ou un produit de purification brute ou de purification d'une fraction de carbonyl réductase obtenue à partir du microbe ou des cellules pour agir sur de la 2-pentanone ou de la 2-hexanone, respectivement.

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