C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/70 (2006.01) A61K 31/445 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01)
Patent
CA 2286242
An industrially excellent process for producing piperidinecarboxylic acid amides which are useful as serotonin antagonists, thrombocytic agents, etc. or intermediates of the same, characterized by reacting 2-oxazoline compounds with piperidine derivatives in the presence of acids.
La présente invention concerne un excellent procédé industriel de production d'amides d'acide pipéridine-carboxylique utilisés comme antisérotonines, agents thrombocytaires, etc., ou intermédiaires de ceux-ci. Ce procédé est caractérisé en ce qu'il consiste à faire réagir des composés 2-oxazoline avec des dérivés de pipéridine en présence d'acides.
Arai Isao
Naora Hirokazu
Yamamoto Takashi
Ajinomoto Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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