Process for producing purine nucleotides

C - Chemistry – Metallurgy – 12 – P

Patent

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Details

C12P 19/40 (2006.01) C07H 21/04 (2006.01) C12N 9/00 (2006.01) C12N 9/12 (2006.01) C12N 9/16 (2006.01) C12P 19/30 (2006.01) C12P 19/32 (2006.01)

Patent

CA 2297613

The present invention provides a process for producing a purine nucleotide which comprises: culturing in a medium a microorganism having the ability to produce a precursor of the purine nucleotide and carrying an introduced DNA which can induce and express an enzyme capable of synthesizing the purine nucleotide from said precursor; allowing said precursor of the purine nucleotide to accumulate in the culture; inducing and expressing the enzyme capable of synthesizing the purine nucleotide from said precursor; allowing the purine nucleotide formed from said precursor to accumulate in said culture; and then recovering said purine nucleotide therefrom. Microorganisms useful in said process are also provided.

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