Process for producing pyridine derivatives having a...

C - Chemistry – Metallurgy – 07 – D

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C07D 213/26 (2006.01) C07D 213/61 (2006.01)

Patent

CA 1125290

ABSTRACT OF THE DISCLOSURE Pyridine derivatives having a trifluoromethyl group in the .beta.-position thereof are produced by reacting .beta.-picoline with chlorine and hydrogen fluoride in the vapor phase at a high temp- erature for a short time. The reaction condition may be mild and the yield of the desired compound is increased by reacting them in the presence of a specific metal fluoride. The pyridine deriva- tives useful as starting materials for agricultural chemicals and medicines can be continuously obtained by a simple reaction at high yield.

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