Process for producing quinoline derivative and intermediate

C - Chemistry – Metallurgy – 07 – D

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C07D 215/12 (2006.01) C07D 215/14 (2006.01)

Patent

CA 2338334

The present invention relates a process for producing the quinoline derivative (3) via the nitrile compound (1) obtained by reacting the aldehyde compound represented by formula (2) with diethyl cyanomethylphosphonate and its intermediate (1).

L'invention concerne un procédé de préparation d'un dérivé (3) de quinoléine, ce procédé étant caractérisé en ce que sa préparation passe par un nitrile (1) qui peut être préparé par réaction d'un aldéhyde (2) avec un phosphonate diéthyl cyanométhyle. L'invention concerne également le produit (1) intermédiaire pour ce procédé.

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