Process for producing quinolinecarbaldehyde

Details Process for producing quinolinecarbaldehyde Process for producing quinolinecarbaldehyde

C - Chemistry, Metallurgy

07

D

C07D 215/14 (2006.01) C07D 319/06 (2006.01)

Patent

CA 2505239

A novel process for producing a quinolinecarbaldehyde (IV) which comprises reacting an aminobenzophenone compound (I) with a .beta.-ketoaldehyde derivative (II) in the presence of an acid to obtain a quinolinecarbaldehyde derivative (III) and then hydrolyzing the quinolinecarbaldehyde derivative; and a process for producing a novel .beta.-ketoaldehyde derivative (II-1) which comprises reacting a metal alkoxide compound (V) with a diol derivative (VI) in the presence of an acid.

L'invention porte sur un nouveau de procédé d'obtention de quinolinecarbaldéhyde (IV) consistant à faire réagir un composé d'aminobenzophénone avec un dérivé de .beta.-cétoaldéhyde (II) en présence d'un acide, pour obtenir un dérivé de quinolinecarbaldéhyde (III) que l'on hydrolyse. L'invention porte également sur un procédé d'obtention d'un nouveau dérivé de .beta.-cétoaldéhyde (II-1) consistant à faire réagir un alcoxyde métallique (V) avec un dérivé de diol en présence d'un acide.

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