Process for producing quinolinecarboxyaldehyde derivative...

Details Process for producing quinolinecarboxyaldehyde derivative... Process for producing quinolinecarboxyaldehyde derivative...

C - Chemistry, Metallurgy

07

D

C07D 215/14 (2006.01) C07D 215/54 (2006.01)

Patent

CA 2437954

2-Cyclopropyl-4-(4'-fluorophenyl)quinoline-3- carboxyaldehyde useful as a material for pharmaceutical products, can be obtained by reacting 3-cyclopropyl-3- oxopropanenitrile with 2-amino-4'-fluorobenzophenone to obtain 2-cyclopropyl-4-(4'-fluorophenyl)quinoline-3- carbonitrile, and reducing it.

L'invention concerne un 2-cyclopropyle-4-(4'-fluorophényle)quinoline-3-carboxyaldéhyde, utile comme matière de départ pour la préparation de médicaments pouvant être obtenu par mise en réaction de 3-cyclopropyle-3-oxopropanenitrile avec une 2-amino-4'-fluorobenzophénone afin de produire un 2-cyclopropyle-4-(4'-fluorophényle)quinoline-3-carbonitrile et par la réduction de ce produit.

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