Process for producing recombinant human serum albumin

C - Chemistry – Metallurgy – 12 – N

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C12N 15/14 (2006.01) C07K 14/765 (2006.01) C12N 1/16 (2006.01) C12N 1/20 (2006.01) C12N 5/02 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2149579

A process for producing recombinant human serum albumin is disclosed, which comprises culturing a human serum albumin-producing host, prepared by gene manipulation techniques in a medium that contains an amino acid, preferably at least one amino acid selected from the group consisting of alanine, aspartic acid, glutamic acid, histidine, serine, tryptophan, valine, isoleucine, phenylalanine, cysteine and arginine, more preferably histidine. The process can significantly increase the yield of human serum albumin over that produced by known processes.

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