Process for producing substituted pyrrole diesters

Details Process for producing substituted pyrrole diesters Process for producing substituted pyrrole diesters

C - Chemistry, Metallurgy

07

D

260/326

C07D 207/34 (2006.01)

Patent

CA 1105039

PROCESS FOR PRODUCING SUBSTITUTED PYRROLE DIESTERS ABSTRACT OF THE DISCLOSURE An improved process for producing substituted pyrrole diesters by reacting a primary amine with an acetone dicarboxylic acid diester and a substituted carbonyl compound such as chloroacetone. The pyrrole ester-forming reaction is conducted in an amine-containing, two-phase, aqueous/organic reaction medium dispersion with which the aceonte dicarboxylic acid ester and substituted carbonyl compound are combined and/or in an amine-containing reaction medium to which the acetone dicarboxylic acid ester and substituted carbonyl compounds are added in a substantially simultaneous manner.

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