Process for producing sustained-release composition

Details Process for producing sustained-release composition Process for producing sustained-release composition

A - Human Necessities

61

K

A61K 47/30 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 9/52 (2006.01) A61K 38/04 (2006.01) A61K 38/09 (2006.01) A61K 45/00 (2006.01) A61K 47/02 (2006.01) A61K 47/06 (2006.01) A61K 47/12 (2006.01) A61K 47/34 (2006.01) A61P 15/00 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2490351

A process for producing a sustained-release composition which comprises mixing an aqueous solution containing a physiologically active substance and an acid or base in a molar amount of 1.5 or more times that of the physiologically active substance with a solution of a biodegradable polymer and then drying the mixture is provided.

La présente invention concerne un procédé de production d'une composition à libération prolongée, qui consiste à mélanger une solution aqueuse contenant une substance physiologiquement active et un acide ou une base en une quantité molaire équivalente à au moins 1,5 fois celle de la substance physiologiquement active avec une solution de polymère biodégradable, et à déshydrater le mélange obtenu.

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