Process for producing trans-4-hydroxy-l-proline

Details Process for producing trans-4-hydroxy-l-proline Process for producing trans-4-hydroxy-l-proline

C - Chemistry, Metallurgy

12

N

C12N 15/53 (2006.01) C12N 1/19 (2006.01) C12N 9/02 (2006.01) C12N 9/06 (2006.01) C12P 13/24 (2006.01)

Patent

CA 2189682

The present invention relates to industrial methods for producing trans-4-hydroxy-L-proline which is useful as a starting compound for medicines and an additive to foods, genes which code for L-proline 4-hydroxylases and which are useful for the above mentioned process, recombinant DNA containing the gene, transformants containing the recombinant DNA, methods for producing L-proline 4-hydroxylases using the transformants and the enzyme.

L'invention porte sur un procédé industriel de production de trans-4-hydroxy-L-proline, substance utilisée dans la synthèse de médicaments ou en tant qu'additif alimentaire; sur un gène de L-proline 4-hydroxylase intervenant dans ledit procédé; sur un ADN de recombinaison contenant ledit gène; sur un transformant contenant ledit ADN, et sur la L-proline 4-hydroxylase obtenue à l'aide dudit transformant, et sur cette enzyme.

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