C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 33/12 (2006.01) C12N 1/14 (2006.01) C12P 33/06 (2006.01)
Patent
CA 2109680
ABSTRACT OF THE DISCLOSURE The invention provides a novel process for the production of 6.beta.,14.alpha.-dihydroxy-4-androstene-3,17-dione which comprises culturing a microorganism belonging to the genus Myrothecium and capable of hydrolyzing 4- androstene-3,17-dione to produce 6.beta.,14.alpha.-dihydroxy-4- androstene-3,17-dione in a medium supplemented with 4- androstene-3,17-dione, and isolating 6.beta.,14.alpha.-dihydroxy-4- androstene-3,17-dione from the cultured medium. Accord- ing to the process of the present invention, 6.beta.,14.alpha.- dihydroxy-4-androstene-3,17-dione and 14.alpha.-hydroxy-4- androstene-3,6,17-trione can be produced with a high yield in a simple manner.
Asada Hajime
Fujita Shinji
Yoshioka Hideki
Marks & Clerk
Nippon Kayaku Kabushiki Kaisha
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