Process for production of amida compound

Details Process for production of amida compound Process for production of amida compound

C - Chemistry, Metallurgy

07

C

C07C 231/10 (2006.01) C07C 221/00 (2006.01) C07C 225/06 (2006.01) C07C 231/12 (2006.01) C07C 231/14 (2006.01) C07C 233/31 (2006.01) C07C 233/47 (2006.01) C07C 233/51 (2006.01) C07C 233/61 (2006.01) C07C 233/63 (2006.01) C07C 233/83 (2006.01) C07C 235/34 (2006.01) C07D 263/42 (2006.01) C07C 233/30 (2006.01)

Patent

CA 2336035

Intermediates for the preparation of phenylalkanoic acid amides having excellent germicidal effects; a process for the preparation of the intermediates; and a process for preparing starting compounds for the preparation of the intermediates. Specifically, a process for the preparation of amides (IV), characterized by reacting a nitrile (I) with an acid to form an oxazolinone (II) through intramolecular cyclization, and reacting this oxazolinone (II) with a carboxyl compound (III) in the presence of a base.

L'invention concerne des intermédiaires entrant dans la préparation d'amides d'acide phénylalcanoïque, qui ont d'excellents effets germicides, ainsi qu'un procédé relatif à leur élaboration et un procédé relatif à l'élaboration de composés de départ pour l'élaboration desdits intermédiaires. Spécifiquement, l'invention concerne un procédé relatif à l'élaboration d'amides (IV) caractérisé par une réaction entre un nitrile (I) et un acide pour former une oxazolinone (II) par cyclisation intramoléculaire, et par une réaction de cette oxazolinone (II) avec un composé carboxyle (III) en présence d'une base.

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