Process for production of amides

C - Chemistry – Metallurgy – 07 – C

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260/556.7

C07C 231/02 (2006.01)

Patent

CA 1183551

PROCESS FOR PRODUCTION OF ? HALOALKYLAMIDES Abstract of the Disclosure Amides having the formula RCCNR2R3 in which R is ?-halo-C1-C8-alkyl; R2 is C1-C8 alkyl, and R3 is C1-C8 alkyl, are prepared by reacting an ester with an amine in the presence of a promoter which is a halide of a Group IIIa metal having a molecular weight of 26 or greater, or of a Group IVb metal. The process is par- ticulaly suitable for production of a desired optical isomer of such an amide.

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