Process for production of eicosapentaenoic acid-containing...

C - Chemistry – Metallurgy – 12 – P

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C12P 13/00 (2006.01) A61K 31/00 (2006.01) A61K 31/66 (2006.01) C12P 7/62 (2006.01) C12P 7/64 (2006.01) C12P 9/00 (2006.01)

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CA 2013614

PROCESS FOR PRODUCTION OF EICOSAPENTAENOIC ACID-CONTAINING PHOSPHOLIPID AND USE OF SAID LIPID ABSTRACT OF THE DISCLOSURE A process for the production of an eicosapentaenoic acid (EPA)-containing phospholipid, comprising the steps of preparing cells of microorganism capable of producing EPA, extracting the cells with a solvent which can solubilize the EPA-containing phospholipid, removing the solvent to obtain a residue containing the EPA con- taining phospholipid mixing the residue with a solvent which substantially cannot solubilize the EPA-containing phospholipid recovering the solvent insoluble fraction, and purify the fraction by column chromatography; and a lipid metabolism modifying composition comprising an EPA-containing phospholipid.

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