C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/351, 204/53
C07D 317/14 (2006.01) C07D 317/20 (2006.01) C07D 317/28 (2006.01) C07D 317/72 (2006.01) C25B 3/00 (2006.01)
Patent
CA 1328459
ABSTRACT OF THE DISCLOSURE A process is disclosed for the production of enantiomer-free 2,2,4-trisubstituted 1,3-dioxolanes of the general formula: Image (I) wherein R1 and R2 are either the same and represent hydrogen, an alkyl group with 1 to 4 C atoms, an aryl group or an arylalkyl group, or R1 and R2 together represent a 1,4-butanediyl or 1,5-pentanediyl group, and X is either a hydroxy group or, in a case in which R1 and R2 are not aryl groups, NHR3 wherein R3 is alkyl with 1 to 8 C atoms or aryl. The process comprises converting a corresponding substituted threonic acid or erythronic acid of the general formula: Image (II) or a salt thereof by electrolysis into the correspondingly substituted 1,3-dioxolane-4-carbaldehyde of the general formula: Image (III) The substituted 1,3-dioxolane-4,-carbaldehyde III is then converted, without isolation by reduction or reductive amination into the enantiomer-free 2,2,4-trisubstituted 1,3-dioxolane of formula I.
588068
G. Ronald Bell & Associates
Lonza Ltd.
LandOfFree
Process for production of enantiomerically pure... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for production of enantiomerically pure..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for production of enantiomerically pure... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1178813