Process for production of insulin-like growth factor i and...

C - Chemistry – Metallurgy – 12 – N

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195/1.2, 195/1.3

C12N 15/17 (2006.01) C07K 14/59 (2006.01) C07K 14/65 (2006.01) C12N 15/70 (2006.01) C12P 21/02 (2006.01)

Patent

CA 1297814

ABSTRACT OF THE DISCLOSURE Preparation of IGF-I fused with a protective peptide. This is carried out by culturing a microorganism trans- formed with an expression plasmid which has a gene coding IGF-I fused with a protective peptide and from which a rop gene is cut off, and recovering IGF-I fused with a protective peptide from the culture broth. There is also described a product which is an expression plasmid which has a gene coding IGF-I fused with a protective peptide and from which a rop gene is cut off. This product is a human insulin-like growth factor.

520933

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