Process for production of l-phenylalanine by fermentation

Details Process for production of l-phenylalanine by fermentation Process for production of l-phenylalanine by fermentation

C - Chemistry, Metallurgy

12

N

195/134, 195/1.3

C12N 15/00 (2006.01) C12N 1/21 (2006.01) C12N 15/52 (2006.01) C12N 15/77 (2006.01) C12P 13/22 (2006.01)

Patent

CA 1283070

ABSTRACT OF THE DISCLOSURE A process for producing L-phenylalanine, which comprises (1) culturing in a culture medium a micro- organism having L-phenylalanine productivity, wherein the microorganism is obtained by incorporating a gene connected with a vector plasmid capable of replicating in cells of a Coryneform glutamic acid-producing bacterium into a recipient bacterium selected from Coryneform glutamic acid-producing bacteria and mutants thereof, wherein the gene when introduced into a mutant induced from a Coryneform glutamic acid-producing bacterium and having auxotrophy for L-phenylalanine is capable of eliminating the auxotrophy of the mutant for L-phenylalanine, and (2) harvesting L-phenylalanine accumulated in the culture medium is disclosed along with bacteria which can be used in carrying out this process.

463704

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