Process for production of novel bis (benzamido)-benzene...

C - Chemistry – Metallurgy – 07 – D

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260/293.3, 260/2

C07D 295/14 (2006.01) C07D 295/08 (2006.01) C07D 295/12 (2006.01)

Patent

CA 1055495

Abstract of the Disclosure: Disclosed herein three processes for producing novel bis(benzamido)-benzene derivatives having various pharma- ceutical properties such as peptic ulcer-preventing and treating, peripheral vasodilating, hypotensive and analgesic activities and represented by the formula: Image (I) wherein X is a direct bond, oxygen, -CONH- or Image wherein R4 is lower alkyl; R1 is straight or branched lower alkylene; R2 and R3 are the same or different lower alkyls, or are bonded to each other directly or through one or more heteroatoms or are bonded to R4; and Y and Z may be the same or different, and each are hydrogen, lower alkyl, hydroxy, lower alkoxy, lower alknoyloxy or halogen.

237612

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