C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/33 (2006.01) A61K 38/16 (2006.01) A61K 47/48 (2006.01)
Patent
CA 2686642
The present invention provides a process for providing a muscle relaxant, wherein said muscle relaxant is a reconstituted solution comprising the neurotoxic component of botulinum toxin free of complexing proteins, which exhibits at least one of the following characteristics, more preferably all characteristics a) to d): a) Stable at storage temperatures above 20°C b) Stable in the presence of preservatives and/or analgesics c) Resistant against "freeze and thaw" - cycles d) Stable if stored in containers of different material.
La présente invention propose un procédé pour fournir un myorelaxant, ledit myorelaxant étant une solution reconstituée comportant le composant neurotoxique de la toxine botulinique exempte de protéines complexantes, qui présente au moins l'une des caractéristiques suivantes, et mieux encore toutes les caractéristiques a) à d) : a) stable aux températures de stockage au-dessus de 20°C; b) stable en présence de conservateurs et/ou d'analgésiques; c) résistant à des cycles de <= congélation et décongélation >=, d) stable si stocké dans des contenants de matériaux différents.
Eisele Karl Heinz
Marx Matthias
Taylor Harold V.
Merz Pharma Gmbh & Co. Kgaa
Sim & Mcburney
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