Process for purification of a cephalosporin derivative

C - Chemistry – Metallurgy – 07 – D

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C07D 501/22 (2006.01) C07D 277/74 (2006.01) C07D 501/00 (2006.01)

Patent

CA 2326441

A process for the purification of cefixime via a novel tert.octylamine salt of a cefixime intermediate which may be crystalline and which may be produced in a one pot reaction from 7-amino-3-vinyl-ceph-3-em-4- carboxylic acid.

L'invention concerne un procédé de purification de céfixime au moyen d'un nouveau sel de ter.octylamine d'un intermédiaire de céfixime pouvant être cristallin et produit dans une réaction en récipient unique à partir d'un acide 7-amino-3-vinyl-ceph-3-em-4-carboxylique.

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