C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 1/16 (2006.01)
Patent
CA 2726823
A method for the purification of a protein, in particular an 1g1v1 antibody, which comprises a chromatography step using a non-ionic polymer (such as hydroxyapatite chromatography and polyethylene glycol as the polymer) to remove protein aggregates, followed by an ion exchange chromatography step using a solubility enhancing additive such as a urea compound, an alkylene glycol or a zwitterion, especially glycine.
L'invention concerne un procédé de purification d'une protéine, en particulier un anticorps IgM, qui comprend une étape de chromatographie utilisant un polymère non ionique (tel qu'une chromatographie à hydroxyapatite et du polyéthylèneglycol en tant que polymère) pour supprimer des agrégats de protéine, ce qui est suivi par une étape de chromatographie à échange d'ions utilisant un additif renforçant la solubilité tel que un composé d'urée, un alkylèneglycol ou un zwitterion, en particulier de la glycine.
Mbm Intellectual Property Law Llp
Patrys Limited
LandOfFree
Process for purification of antibodies does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for purification of antibodies, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for purification of antibodies will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1780240