Process for racemization of [2-(2-thienyl)ethylamino]...

C - Chemistry – Metallurgy – 07 – D

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C07D 333/20 (2006.01) C07D 221/00 (2006.01) C07D 333/00 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2347853

The invention relates to the racemization process of the optically active [2- (2thienyl)ethylamino](2-halogenophenyl)acetamides of general formula (VII) by using basic compounds. The resulting racemic compounds of general formula (VII) can thus be recycled into synthesis of the therapeutically useful compounds of general formula (VI).

L'invention concerne un procédé de racémisation des acétamides [2-(2-thiényl) éthylamino](2-halogenophényl) actifs en termes optiques de formule générale (VII) à l'aide de composés. Les composés racémiques obtenus de formule générale (VII) peuvent donc être recyclés et transformés en synthèse des composés thérapeutiquement utiles de formule générale (VI).

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