A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/36 (2006.01) A61F 2/24 (2006.01)
Patent
CA 2345799
The present invention provides a method for reducing the level of mineralization of tissue in a tissue--derived implantable medical device. Preferably, the method reduces the level of bioprosthetic valvular mineralization, and in particular bioprosthetic valvular pathologic calcification. A method of making a tissue-derived implantable medical device includes contacting the tissue with a composition comprising at least one oxidizing agent prior to implantation of the medical device. The tissue--derived implantable medical device treated by a method of the invention exhibits improved anti-mineralization properties, and/or longer term resistance to in vivo pathologic calcification than provided by other methods of reducing and/or preventing mineralization.
La présente invention concerne un procédé permettant de réaliser un dispositif médical implantable à base de tissu. Ce procédé consiste à mettre le tissu en contact avec une composition renfermant au moins un agent oxydant avant implantation du dispositif médical.
Medtronic Inc.
Smart & Biggar
Torrianni Mark W.
LandOfFree
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