C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 271/22 (2006.01) C07B 41/02 (2006.01) C07B 53/00 (2006.01) C07C 29/143 (2006.01) C07C 213/00 (2006.01) C07C 269/06 (2006.01) C07C 271/16 (2006.01) C07C 319/20 (2006.01) C07C 323/43 (2006.01)
Patent
CA 2216537
The present invention provides a process for reducing carbonyl compounds to hydroxy compounds, in particular stereoselectively reducing .alpha. -aminohaloketone derivatives, under mild conditions in an easy and simple manner, which comprises reacting a carbonyl compound of the general formula (1) with an organoaluminum compound of the general formual (4) to provide the corresponding alcohol compound of the general formula (5). (see fig. I) (see fig. II) (see fig. III)
L'invention a trait à des procédés permettant une réduction de composés de carbonyle en composés hydroxylés, facilement et dans des conditions relativement plus douces que celles que ne le permettaient les techniques jusqu'alors utilisées. Elle porte, notamment, sur un procédé de réduction stéréosélective d'un dérivé d'.alpha.-aminohalocétone. Ledit procédé consiste à traiter un composé de carbonyle répondant à la formule générale (1) à l'aide d'un composé organoaluminé répondant à la formule générale (4) afin de former un alcool répondant à la formule générale (5).
Inoue Kenji
Kan Kazunori
Moroshima Tadashi
Sugawa Tadashi
Kaneka Corporation
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