Process for removing viruses in fibrinogen solutions and...

Details Process for removing viruses in fibrinogen solutions and... Process for removing viruses in fibrinogen solutions and...

A - Human Necessities

61

K

A61K 38/36 (2006.01) A61L 2/00 (2006.01) B01D 37/00 (2006.01) B01D 61/14 (2006.01) C07K 1/34 (2006.01) C07K 14/75 (2006.01) C12N 7/02 (2006.01)

Patent

CA 2459690

The process starts with an adjusted purified fibrinogen solution, the adjusted purified solution is frozen and then thawed at a temperature between 5 and 20°C, the undissolved materials associated with the fibrinogen are subsequently separated, the temperature is adjusted and the resultant solution is finally subjected to nanofiltration using filters to a pore size smaller than 35 mm.

Le processus commence avec une solution de fibrinogène purifiée et ajustée; cette solution est congelée, puis décongelée jusqu'à l'atteinte d'une température se situant entre 5 et 20 degrés Celsius; ensuite, les matières non dissoutes associées avec le fibrinogène sont séparées, la température est ajustée, et la solution obtenue subit finalement une nanofiltration sur filtres dont les pores ont une taille inférieure à 35 mm.

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