Process for replicating bone marrow and other tissues in...

Details Process for replicating bone marrow and other tissues in... Process for replicating bone marrow and other tissues in...

A - Human Necessities

61

K

167/104, 150/13,

A61K 35/28 (2006.01) A61B 19/00 (2006.01) A61K 35/36 (2006.01) A61K 35/407 (2006.01) C12N 5/00 (2006.01) C12N 5/08 (2006.01) G01N 33/48 (2006.01) G01N 33/53 (2006.01)

Patent

CA 1310926

ABSTRACT A process for treating a person whose bone marrow has been destroyed or has lost its functional ability, which includes the steps of obtaining bone marrow from a donor, replicating the bone marrow cells in vitro, and then reinfusing the replicated marrow cells at a later date. The bone marrows may be cryopreserved before and/or after the replication step. The in vitro bone marrow replication system may also be used to monitor a patient's condition or the cytotoxicity of various agents. Three-dimensional cell culture systems for the growth of at least two layers of cells, for cell types in addition to bone marrow cells, may also be established using a three-dimensional support as a framework.

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