Process for resolution of tamsulosin

Details Process for resolution of tamsulosin Process for resolution of tamsulosin

C - Chemistry, Metallurgy

07

C

C07C 311/38 (2006.01) C07B 57/00 (2006.01)

Patent

CA 2464648

Optically impure tamsulosin including racemic tamsulosin can be resolved into optically pure (R)- or (S)-tamsulosin by the use of diastereomeric sulfonate salts of tamsulosin in a fractional crystallization technique.

La tamsulosine optiquement impure, notamment la tamsulosine racémique, peut être résolue en une tamsulosine (R) ou (S), au moyen de sels de sulfonate diastéréomériques de tamsulosine, et ce dans le cadre d'une technique de cristallisation sélective.

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