Process for resolving zopiclone

Details Process for resolving zopiclone Process for resolving zopiclone

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/4985 (2006.01)

Patent

CA 2742725

The present invention provides a process for the preparation of the dextrorotatory isomer of zopiclone (eszopiclone). The present invention also provides eszopiclone di-p-anisolyl-L- tartrate and eszopiclone diacetyl-L-tartrate, which are useful as intermediates in a process for preparing eszopiclone.

La présente invention porte sur un procédé pour la préparation de l'isomère dextrogyre de la zopiclone (l'eszopiclone). La présente invention porte également sur le di-p-anisolyl-L-tartrate d'eszopiclone et le diacétyl-L-tartrate d'eszopiclone, qui sont utiles comme intermédiaires dans un procédé pour la préparation d'eszopiclone.

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