Process for solid phase synthesis

Details Process for solid phase synthesis Process for solid phase synthesis

B - Operations, Transporting

01

F

B01F 7/24 (2006.01) B01J 8/10 (2006.01) B01J 19/20 (2006.01) B01J 19/28 (2006.01)

Patent

CA 2370669

A reactor vessel for carrying out solid phase synthesis, particularly the solid phase synthesis of oligonucleotides, peptides, and combinatorial chemistry is provided. The reactor vessel comprises two or more orifices spaced from one another through which liquids within the vessel can be discharged and has a mounting (4) enabling the vessel to be rotated about an axis so that each orifice can be moved into and out of a discharge position. Each orifice is adapted for closure by removable filtration means (7) which are secured to the vessel to filter liquids discharging through the orifice when the orifice is in the discharge position. Processes for replacing the filtration means (7) and for solid phase synthesis employing the use of an agitator with helical blades are provided.

La présente invention concerne un réacteur destiné à mettre en oeuvre de la synthèse en phase solide, en particulier de la synthèse en phase solide d'oligonucléotides, de peptides et de chimie combinatoire. Le réacteur comprend deux ou plusieurs orifices, espacés les uns des autres, au travers desquels il est possible de déverser des liquides contenus à l'intérieur. Ce réacteur est doté d'un montage permettant sa rotation autour d'un axe de telle manière que chaque orifice puisse être hors et en position de déversement. Chaque orifice est adapté de façon à permettre sa fermeture au moyen de filtres amovibles fixés au réacteur afin de filtrer des liquides qui sortent de l'orifice lorsque celui ci est en position de déversement. L'invention concerne aussi des procédés de synthèse en phase solide utilisant un agitateur ainsi que des procédés destinés à remplacer les moyens de filtration.

Affiliated with

Also associated with

Rating

Process for solid phase synthesis does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for solid phase synthesis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for solid phase synthesis will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1827569