Process for synthesis of 4-4'-diamino-diphenyl-sulfone

C - Chemistry – Metallurgy – 07 – C

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C07C 315/02 (2006.01)

Patent

CA 2573114

A new process for the preparation and purification of 4-4'-diamino-diphenyl- sulfone (dapsone) is described. The process described is a three step process comprising a condensation reaction with the synthesis of a thioeter intermediate and then steps of oxidation and reduction in suitable conditions in order to obtain a product with good yield and purity.

La présente invention concerne un nouveau processus de préparation de purification de of 4-4'-diamino-diphényl-sulfone (dapsone). Ce processus est un processus en trois étapes qui comprend une réaction de condensation avec la synthèse d'un intermédiaire thioéter puis les étapes d'oxydation et de réduction dans des conditions convenables de façon à obtenir un produit avec un bon rendement est une bonne pureté.

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