Process for synthesizing anhydroecgonine derivative

Details Process for synthesizing anhydroecgonine derivative Process for synthesizing anhydroecgonine derivative

C - Chemistry, Metallurgy

07

D

C07D 451/02 (2006.01) C07K 5/083 (2006.01)

Patent

CA 2331029

The present invention relates to a process for synthesizing an anhydroecgonine derivative without using cocaine as a starting material, and a process for synthesizing a phenyltropane derivative by using said anhydroecgonine derivative as an intermediate for the synthesis. The present invention provides a process for synthesizing an anhydroecgonine derivative which comprises reacting a cycloheptatriene derivative represented by the formula (1): (see formula 1) with a primary amine, a salt thereof or ammonia in the presence of a base to obtain an anhydroecgonine derivative, and a process for synthesizing a phenyl- tropane derivative by using said anhydroecgonine derivative. In the formula (1), n is an integer of 0 or 1; and R1 is a cyano group in the case of n being 0, and R1 is selected from an alkyl group and an aralkyl group in the case of n being 1.

Affiliated with

Also associated with

Rating

Process for synthesizing anhydroecgonine derivative does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for synthesizing anhydroecgonine derivative, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for synthesizing anhydroecgonine derivative will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1981787