Process for synthesizing compounds useful for treating...

Details Process for synthesizing compounds useful for treating... Process for synthesizing compounds useful for treating...

C - Chemistry, Metallurgy

07

D

C07D 403/14 (2006.01)

Patent

CA 2695711

The present disclosure generally relates to a process for synthesizing methyl ((1S)-1-(((2S)-2-(5-(4'-(2--((2S)-1-((2S)-2-((methoxycarbonyl)amino)-3- methylbutanoyl)-2-pyrrolidinyl)-1H-imidazol-5-yl)-4-biphenylyl)-1H-imidazol-2- yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt. The present disclosure also generally relates to intermediates useful in this process.

D'une manière générale, la présente invention concerne un procédé de synthèse de sel de dihydrochlorure de méthyl ((1S)-1-(((2S)-2-(5-(4'-(2-((2S)-1-((2S)-2-((méthoxycarbonyl)amino)-3-méthylbutanoyl)-2-pyrrolidinyl)-1H-imidazol-5-yl)-4-biphénylyl)-1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-méthylpropyl)carbamate. D'une manière générale, la présente invention concerne également des intermédiaires utiles dans ce procédé.

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